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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK [C481S]' and Ligand = 'BDBM412879'
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Loxo Oncology

US Patent
LigandPNGBDBM412879(US10399989, Example 92)
Affinity DataIC50: <10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent