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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM116313'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM116313(US8637526, 231)
Affinity DataKi:  15.2nMpH: 7.2Assay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 1.5 nM JAK1, 0.2 nM pu...More data for this Ligand-Target Pair
In DepthDetails US Patent