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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50312977'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50312977(7-(4-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)benz...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of GST-tagged JAK1 assessed as inhibition of biotinylated IRS1 substrate phosphorylation after 60 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed