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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1 [837-1142]' and Ligand = 'BDBM400487'
TargetTyrosine-protein kinase JAK1 [837-1142](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM400487(Diastereomers of 3-[(4-{3-(cyanomethyl)-3-[4-(7H-p...)
Affinity DataIC50: <5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [837-1142](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM400487(Diastereomers of 3-[(4-{3-(cyanomethyl)-3-[4-(7H-p...)
Affinity DataIC50: <10nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent