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Found 9 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM192755'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  1.40nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  1.80nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataIC50:  97.6nMAssay Description:The HotSpot Kinase Assay is used at our US facility for compound screening on protein kinases.More data for this Ligand-Target Pair