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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM198631'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical Industries

US Patent
LigandPNGBDBM198631(US9216999, 424 | US9556187, Example 424)
Affinity DataIC50:  480nMT: 2°CAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical Industries

US Patent
LigandPNGBDBM198631(US9216999, 424 | US9556187, Example 424)
Affinity DataIC50:  480nMpH: 7.5Assay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent