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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM270734'
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM270734
(US10059705, II-129)
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Affinity Data
IC50: 1.49E+3nM
T: 2°C
Assay Description:
The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...
More data for this Ligand-Target Pair
Target Info
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Reactome pathway
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Ligand Info
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US Patent
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