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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM294511'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Hutchison Medipharma

US Patent
LigandPNGBDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50:  0.5nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Hutchison Medipharma

US Patent
LigandPNGBDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent