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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [828-1132]' and Ligand = 'BDBM246877'
TargetTyrosine-protein kinase JAK2 [828-1132](Homo sapiens (Human))
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US Patent
LigandPNGBDBM246877(4-{3-(cyanomethyl)- 3-[4-(7H-pyrrolo[2,3- d]pyrimi...)
Affinity DataIC50: <10nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), JAK2 (a.a. 828-1132) and JAK3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent