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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM309788'
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Pharmacyclics
US Patent
Ligand
BDBM309788
((R)-3-(4-(1-ethylpiperidin-4-yl)phenylamino)-5-(3-...)
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Affinity Data
IC50: 55nM
Assay Description:
The degree of inhibition of a panel of kinases is determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate subst...
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Target Info
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Ligand Info
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Details
US Patent
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