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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM364420'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM364420(US9862688, Compound 6)
Affinity DataIC50:  5.90nMAssay Description:The in vitro activity of the compounds described herein in inhibiting JAK3 and other kinases were obtained using an INVITROGEN Select Screening assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM364420(US9862688, Compound 6)
Affinity DataIC50:  38nMAssay Description:The in vitro activity of the compounds described herein in inhibiting JAK3 and other kinases were obtained using an INVITROGEN Select Screening assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent