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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM413455'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM413455((R)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitory activity of compounds against AURKA, AURKB, JAK1, JAK2 and JAK3 was determined in Z'-LYTE?? assays run by ThermoFisher Scientific ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM413455((R)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]py...)
Affinity DataIC50: <1.00E+4nMAssay Description:The inhibitory activity of compounds against AURKA, AURKB, JAK1, JAK2 and JAK3 was determined in Z′-LYTE?? assays run by ThermoFisher Scientifi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent