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Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50092225'
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 uM ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  14nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  14nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092225(7-tert-Butyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  75nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed