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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase TXK' and Ligand = 'BDBM384543'
Target
Tyrosine-protein kinase TXK
(Homo sapiens (Human))
Principia Biopharma
US Patent
Ligand
BDBM384543
((R)-N-(1-((1-acryloylpyrrolidin-2-yl)methyl)-5-(((...)
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Affinity Data
IC50: 0.300nM
Assay Description:
The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...
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Target Info
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Ligand Info
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US Patent
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