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Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50118779'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118779(3-(Oxalyl-amino)-thiophene-2-carboxylic acid | 3-(...)
Affinity DataKi:  3.69E+4nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118779(3-(Oxalyl-amino)-thiophene-2-carboxylic acid | 3-(...)
Affinity DataKi:  3.70E+4nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118779(3-(Oxalyl-amino)-thiophene-2-carboxylic acid | 3-(...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118779(3-(Oxalyl-amino)-thiophene-2-carboxylic acid | 3-(...)
Affinity DataKi:  3.72E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed