Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 22' and Ligand = 'BDBM50031906'
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataKi: 2.87E+3nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataEC50: 6.49E+3nMAssay Description:Inhibition of Lyp in antiCD3-antibody-stimulated human Jurkat T cells assessed as activation of TCR-mediated and IL-2 promoter driven NFAT/AP1 transc...More data for this Ligand-Target Pair