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Found 5 Enz. Inhib. hit(s) with Target = 'Urease subunit beta' and Ligand = 'BDBM34233'
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataKi:  226nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataIC50:  4.54E+4nMAssay Description:Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate after 2 hrs by Berthelot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed