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Found 3 Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50003991'
LigandPNGBDBM50003991(CHEMBL2180008 | US10562916, Compound 204 | US98345...)
Affinity DataIC50: <500nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50003991(CHEMBL2180008 | US10562916, Compound 204 | US98345...)
Affinity DataIC50: <500nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM50003991(CHEMBL2180008 | US10562916, Compound 204 | US98345...)
Affinity DataIC50: <500nMAssay Description:The activities of the compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 e...More data for this Ligand-Target Pair
In DepthDetails US Patent