Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50042058'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)
Affinity DataIC50:  50nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)
Affinity DataIC50:  300nMAssay Description:Inhibition activity against human monocyte derived PDE4 catalytic activity (LPDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of partially-purified PDE 4 from human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed