Compile Data Set for Download or QSAR
maximum 50k data
Found 62 Enz. Inhib. hit(s) with all data for entry = 6526
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293091(7-({[(1R,2S)-2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL...)
Affinity DataKd:  0.00860nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293060(7-{(1S)-1-[(1,3-Dihydroxypropan-2-yl)amino]-2-hydr...)
Affinity DataKd:  297nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293068(7-{[(2-Hydroxyethyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  1.10nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293077(7-{[(4-Hydroxybutyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  25nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293075(7-({[3-Hydroxy-2-(hydroxymethyl)propyl]amino}methy...)
Affinity DataKd:  14.1nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293070(7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)ami...)
Affinity DataKd:  3.70nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293064(7-({[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]am...)
Affinity DataKd:  0.620nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136302(US8853224, 12 | US9290501, MT-TrisMe-ImmH)
Affinity DataKd:  3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293076(7-({[(2R)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  14.9nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136303(US8853224, 3.4)
Affinity DataKd:  300nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293079(7-({[(2S)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  165nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293071(7-({[(2S)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  4.20nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293081(7-({[(2R)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  96nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293073(7-({[(2S,3S)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  5.20nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293072(7-({[(2R,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  4.30nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293067(7-({[(2S,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  1nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293078(7-({[(2S,3R)-2,3,4-Trihydroxybutyl]amino}methyl)-3...)
Affinity DataKd:  31nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136304(US8853224, 20.5)
Affinity DataKd:  84nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293083(7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methy...)
Affinity DataKd:  227nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293085(7-({[(2R/S,3S/R)-3,4-Dihydroxy-2-(hydroxymethyl)bu...)
Affinity DataKd:  0.780nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136305(US8853224, 22)
Affinity DataKd:  900nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136306(US8853224, 24)
Affinity DataKd:  15nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136307(US8853224, 25)
Affinity DataKd:  74nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136308(US8853224, 26)
Affinity DataKd:  71nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136309(US8853224, 27)
Affinity DataKd:  142nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136310(US8853224, 28)
Affinity DataKd:  5.60nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136311(US8853224, 23)
Affinity DataKd:  159nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136312(US8853224, 29)
Affinity DataKd:  22nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136313(US8853224, 19)
Affinity DataKd:  51nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM136314(US8853224, 20.8)
Affinity DataKd:  789nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

US Patent
LigandPNGBDBM50293060(7-{(1S)-1-[(1,3-Dihydroxypropan-2-yl)amino]-2-hydr...)
Affinity DataKd:  0.210nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293068(7-{[(2-Hydroxyethyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  430nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293077(7-{[(4-Hydroxybutyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  770nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293075(7-({[3-Hydroxy-2-(hydroxymethyl)propyl]amino}methy...)
Affinity DataKd:  210nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293070(7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)ami...)
Affinity DataKd:  2.00E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293064(7-({[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]am...)
Affinity DataKd:  163nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM136302(US8853224, 12 | US9290501, MT-TrisMe-ImmH)
Affinity DataKd:  4.30E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293063(7-{[(1,3-Dihydroxypropan-2-yl)(2-hydroxyethyl)amin...)
Affinity DataKd:  1.00E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293076(7-({[(2R)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  1.80E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM136303(US8853224, 3.4)
Affinity DataKd:  2.00E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293079(7-({[(2S)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  550nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293071(7-({[(2S)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  260nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293081(7-({[(2R)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  1.38E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293073(7-({[(2S,3S)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  4.80E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293072(7-({[(2R,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  770nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293091(7-({[(1R,2S)-2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL...)
Affinity DataKd:  55nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293067(7-({[(2S,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  210nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293078(7-({[(2S,3R)-2,3,4-Trihydroxybutyl]amino}methyl)-3...)
Affinity DataKd:  1.20E+4nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM136304(US8853224, 20.5)
Affinity DataKd:  3.20E+4nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293083(7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methy...)
Affinity DataKd:  770nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
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