Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50030370
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  0.600nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)
Affinity DataKi:  2nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataKi:  2.40nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to human histamine H3 receptor by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  4.80nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataKi:  12nMAssay Description:Binding affinity to rat histamine H3 receptor by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM22530(N(alpha)-Methylhistamine | N-alpha-methylhistamine...)
Affinity DataKi:  19nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Affinity DataKi:  68nMAssay Description:Displacement of 3-([1,1,1-3H]methyl)-2-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone from mouse histamine H3 receptor expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to histamine H3 receptor in wild type mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataEC50:  11nMAssay Description:Inverse agonist activity at mouse histamine H3 receptor overexpressed in HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataEC50:  1.70nMAssay Description:Inverse agonist activity at mouse histamine H3 receptor overexpressed in HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataEC50:  9.60nMAssay Description:Inverse agonist activity at mouse histamine H3 receptor overexpressed in HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246289(3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)q...)
Affinity DataKd:  2.60nMAssay Description:Binding affinity to mouse histamine H3 receptor overexpressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed