Compile Data Set for Download or QSAR
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Found 74 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 1771
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339807(US9757364, Compound 11)
Affinity DataIC50:  0.126nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339838(US9757364, Compound 39)
Affinity DataIC50:  0.603nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339822(US9757364, Compound 15)
Affinity DataIC50:  0.759nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339823(US9757364, Compound 16)
Affinity DataIC50:  1.29nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339871(US9757364, Compound 55)
Affinity DataIC50:  1.41nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339869(US9757364, Compound 57)
Affinity DataIC50:  1.45nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339868(US9757364, Compound 62)
Affinity DataIC50:  1.45nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339848(US9757364, Compound 47)
Affinity DataIC50:  1.45nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339873(US9757364, Compound 59)
Affinity DataIC50:  1.55nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339803(US9757364, Compound 10)
Affinity DataIC50:  1.58nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339846(US9757364, Compound 46)
Affinity DataIC50:  1.82nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339837(US9757364, Compound 40 | US9757364, Compound 43)
Affinity DataIC50:  1.86nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339840(US9757364, Compound 37 | US9757364, Compound 41)
Affinity DataIC50:  1.86nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339843(US9757364, Compound 42 | US9757364, Compound 44)
Affinity DataIC50:  1.95nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339843(US9757364, Compound 42 | US9757364, Compound 44)
Affinity DataIC50:  2.09nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339849(US9757364, Compound 48)
Affinity DataIC50:  2.09nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339837(US9757364, Compound 40 | US9757364, Compound 43)
Affinity DataIC50:  2.14nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339866(US9757364, Compound 58)
Affinity DataIC50:  2.19nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339825(US9757364, Compound 31)
Affinity DataIC50:  2.19nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339839(US9757364, Compound 38)
Affinity DataIC50:  2.24nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339799(US9757364, Compound 3)
Affinity DataIC50:  2.51nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339847(US9757364, Compound 45)
Affinity DataIC50:  2.82nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339840(US9757364, Compound 37 | US9757364, Compound 41)
Affinity DataIC50:  2.88nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339852(US9757364, Compound 50)
Affinity DataIC50:  2.88nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339870(US9757364, Compound 61)
Affinity DataIC50:  2.95nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339841(US9757364, Compound 36)
Affinity DataIC50:  3.02nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339824(US9757364, Compound 27)
Affinity DataIC50:  3.02nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339798(US9757364, Compound 1)
Affinity DataIC50:  3.16nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339804(US9757364, Compound 2)
Affinity DataIC50:  3.16nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339850(US9757364, Compound 49)
Affinity DataIC50:  3.16nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339819(US9757364, Compound 13)
Affinity DataIC50:  3.24nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339817(US9757364, Compound 21)
Affinity DataIC50:  3.39nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339829(US9757364, Compound 29)
Affinity DataIC50:  3.39nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339857(US9757364, Compound 72)
Affinity DataIC50:  3.55nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339828(US9757364, Compound 30)
Affinity DataIC50:  3.63nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339836(US9757364, Compound 34)
Affinity DataIC50:  3.72nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339818(US9757364, Compound 12)
Affinity DataIC50:  3.72nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339811(US9757364, Compound 65)
Affinity DataIC50:  3.72nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339812(US9757364, Compound 26)
Affinity DataIC50:  3.72nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339855(US9757364, Compound 53)
Affinity DataIC50:  3.80nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339867(US9757364, Compound 63)
Affinity DataIC50:  3.89nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339801(US9757364, Compound 4)
Affinity DataIC50:  3.98nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339805(US9757364, Compound 7)
Affinity DataIC50:  3.98nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339806(US9757364, Compound 8)
Affinity DataIC50:  3.98nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339834(US9757364, Compound 35)
Affinity DataIC50:  4.37nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339853(US9757364, Compound 51)
Affinity DataIC50:  4.68nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339872(US9757364, Compound 60)
Affinity DataIC50:  4.90nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339835(US9757364, Compound 32)
Affinity DataIC50:  5.01nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339800(US9757364, Compound 6)
Affinity DataIC50:  5.01nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339802(US9757364, Compound 5)
Affinity DataIC50:  5.01nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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