Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50030618
TargetEphrin type-B receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of EphB1 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EphB2 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of EphA2 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of EphA1 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 5(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EphA5 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of EphA4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 8(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of EphA8 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  5nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  15nMAssay Description:Inhibition of EphB3 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of EphA3 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299219(8-(2-Methoxyphenyl)-1-methyl-7-o-methylphenyl-1H-i...)
Affinity DataIC50:  47nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299219(8-(2-Methoxyphenyl)-1-methyl-7-o-methylphenyl-1H-i...)
Affinity DataIC50:  180nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299220(8-(2-Methoxyphenyl)-1-methyl-7-m-hydroxyphenyl-1H-...)
Affinity DataIC50:  213nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299221(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-4'-hydro...)
Affinity DataIC50:  236nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299220(8-(2-Methoxyphenyl)-1-methyl-7-m-hydroxyphenyl-1H-...)
Affinity DataIC50:  368nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299222(8-(Butyl)-1-methyl-7-p-hydroxyphenyl-1H-imidazo[2,...)
Affinity DataIC50:  558nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299223(8-(Butyl)-1-methyl-7-m-hydroxyphenyl-1H-imidazo[2,...)
Affinity DataIC50:  691nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 7(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of EphA7 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299224(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-3'-hydro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299225(8-(Butyl)-1-methyl-7-o-hydroxyphenyl-1H-imidazo[2,...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299226(8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299226(8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1...)
Affinity DataIC50:  4.35E+3nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299227(8-(2-Methoxyphenyl)-1-methyl-7-(2',5'-dihydroxyphe...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299228(7-p-Fluorophenyl-8-(2-methoxyphenyl)-1H-imidazo[2,...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50:  5.68E+3nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299232(1-Benzyl-8-(2-methoxyphenyl)-7-phenyl-1H-imidazo[2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299236(8-(2-Methoxyphenyl)-1-methyl-7-m-methylphenyl-1H-i...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299235(8-(Butyl)-1-methyl-7-p-methoxyphenyl-1H-imidazo[2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299234(8-(Butyl)-1-methyl-7-o-methoxyphenyl-1H-imidazo[2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299233(1-Benzyl-7-p-fluorophenyl-8-(2-methoxyphenyl)-1H-i...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299237(7-(Benzo[d][1,3]dioxol-5-yl)-8-(2-methoxyphenyl)-1...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299231(8-(2-Methoxyphenyl)-1-methyl-7-p-carboxyphenyl-1H-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299230(8-(2-Methoxyphenyl)-1-methyl-7-p-cyanophenyl-1H-im...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299229(8-(2-Methoxyphenyl)-1-methyl-7-p-nitrophenyl-1H-im...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed