TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of EGFR (unknown origin) using biotin-labelled peptide as substrate preincubated for 2 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of cathepsin C (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 135nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 221nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 271nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 307nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 392nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 483nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 499nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 505nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 537nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 783nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair