Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50258884
Substrate
n/a
Meas. Tech.
ChEBML_1690747
Ki
7.2±n/a nM
Citation
 Azuaje, J; Jespers, W; Yaziji, V; Mallo, A; Majellaro, M; Caamaño, O; Loza, MI; Cadavid, MI; Brea, J; Åqvist, J; Sotelo, E; Gutiérrez-de-Terán, H Effect of Nitrogen Atom Substitution in A J Med Chem 60:7502-7511 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50258884
Synonyms:
CHEMBL4097170
Type:
Small organic molecule
Emp. Form.:
C23H20N2O3
Mol. Mass.:
372.4165
SMILES:
CC(=O)Nc1cc(cc(n1)-c1ccc(cc1)C(C)=O)-c1ccc(cc1)C(C)=O
Structure:
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