Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50258891
Substrate
n/a
Meas. Tech.
ChEBML_1690747
Ki
2.8±n/a nM
Citation
 Azuaje, J; Jespers, W; Yaziji, V; Mallo, A; Majellaro, M; Caamaño, O; Loza, MI; Cadavid, MI; Brea, J; Åqvist, J; Sotelo, E; Gutiérrez-de-Terán, H Effect of Nitrogen Atom Substitution in A J Med Chem 60:7502-7511 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50258891
Synonyms:
CHEMBL4067466
Type:
Small organic molecule
Emp. Form.:
C21H16N2O5
Mol. Mass.:
376.3621
SMILES:
CC(=O)Nc1cc(cc(n1)-c1ccc2OCOc2c1)-c1ccc2OCOc2c1
Structure:
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