Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50159488
Substrate
n/a
Meas. Tech.
ChEMBL_1913508 (CHEMBL4416091)
Ki
2.0±n/a nM
Citation
 Mallo-Abreu, A; Majellaro, M; Jespers, W; Azuaje, J; Caamaño, O; García-Mera, X; Brea, JM; Loza, MI; Gutiérrez-de-Terán, H; Sotelo, E Trifluorinated Pyrimidine-Based A J Med Chem 62:9315-9330 (2019) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50159488
Synonyms:
CHEMBL3787197
Type:
Small organic molecule
Emp. Form.:
C19H19N3O3
Mol. Mass.:
337.3725
SMILES:
CC(C)OC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1ccco1 |c:6|
Structure:
Search PDB for entries with ligand similarity: