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Target
Peptide deformylase
Ligand
BDBM50535516
Substrate
n/a
Meas. Tech.
ChEMBL_1930889 (CHEMBL4434140)
Ki
60±n/a nM
Citation
 Spletstoser, JT; Dreabit, J; Knox, AN; Benowitz, A; Campobasso, N; Ward, P; Cui, G; Lewandowski, T; McCloskey, L; Aubart, KM Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections. Bioorg Med Chem Lett 29:2410-2414 (2019) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50535516
Synonyms:
CHEMBL4542964
Type:
Small organic molecule
Emp. Form.:
C20H35N3O5
Mol. Mass.:
397.509
SMILES:
CCC(=O)[C@@H](NC(=O)[C@@H]1CCCNN1C(=O)[C@H](CC(C)C)CC(O)=O)C(C)C |r|
Structure:
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