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Target
D(3) dopamine receptor
Ligand
BDBM50609164
Substrate
n/a
Meas. Tech.
ChEMBL_2276723
Ki
3.4±n/a nM
Citation
 Mallo-Abreu, A; Reyes-Resina, I; Azuaje, J; Franco, R; García-Rey, A; Majellaro, M; Miranda-Pastoriza, D; García-Mera, X; Jespers, W; Gutiérrez-de-Terán, H; Navarro, G; Sotelo, E Potent and Subtype-Selective Dopamine D J Med Chem 64:8710-8726 (2021) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_HUMAN | Dopamine D3 receptor
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Homo sapiens
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50609164
Synonyms:
CHEMBL5289063
Type:
Small organic molecule
Emp. Form.:
C25H29N5O3
Mol. Mass.:
447.5295
SMILES:
Oc1ccc(N2CCCN(CCCCOc3ccc4ccnn4c3)CC2)c2ccc(=O)[nH]c12
Structure:
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