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Target
Beta-lactamase
Ligand
BDBM50021959
Substrate
n/a
Meas. Tech.
ChEMBL_522056 (CHEMBL1004914)
IC50
72800±n/a nM
Citation
 Fonseca, F; Sarmento, AC; Henriques, I; Samyn, B; van Beeumen, J; Domingues, P; Domingues, MR; Saavedra, MJ; Correia, A Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. Antimicrob Agents Chemother 51:4512-4 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Carbapenem-hydrolizing beta-lactamase SFC-1
Type:
PROTEIN
Mol. Mass.:
33593.82
Organism:
Serratia fonticola
Description:
ChEMBL_522056
Residue:
309
Sequence:
MSRTGRLSVFFSAIFPLLTLTNMAEAASQPPQVTVDKLKRLENDFGGRIGVYAIDTGSNKTFGYRANERFPLCSSFKGFLAAAVLSKSQQQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKLIGGPEGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERHQLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGVYGTANDYAVIWPVGHAPIVLAVYTSKPDKNSKHSDAVIADASRIVLESFNIDALRMATGKSIGF
  
Inhibitor
Name:
BDBM50021959
Synonyms:
CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid
Type:
Small organic molecule
Emp. Form.:
C8H9NO5
Mol. Mass.:
199.1608
SMILES:
OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r|
Structure:
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