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Target
Thyrotropin-releasing hormone receptor
Ligand
BDBM50261685
Substrate
n/a
Meas. Tech.
ChEMBL_533265 (CHEMBL973283)
IC50
23000±n/a nM
Citation
 Carroll, AR; Urban, S; Lamb, J; Moni, R; Guymer, GP; Forster, PI; Quinn, RJ Corymbones A and B, phloroglucinols with thyrotropin releasing hormone receptor 2 binding affinity from the flowers of Corymbia peltata. J Nat Prod 71:881-3 (2008) [PubMed]  Article 
Target
Name:
Thyrotropin-releasing hormone receptor
Synonyms:
Thyrotropin-releasing hormone receptor 2
Type:
PROTEIN
Mol. Mass.:
39044.21
Organism:
Rattus norvegicus
Description:
ChEMBL_532304
Residue:
352
Sequence:
MDGPSNVSLIHGDTTLGLPEYKVVSVFLVLLVCTLGIVGNAMVILVVLTSRDMHTPTNCYLVSLALADLLVLLAAGLPNVSDSLVGHWIYGRAGCLGITYFQYLGINVSSFSILAFTVERYIAICHPLRAQTVCTVARAKRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVPRGLYLPIYLLDFAVFFIGPLLVTLVLYGLIGRILFQSPLSQEAWQKERQPHGQSEAAPGNCSRAKSSRKQATRMLAVVVLLFAVLWTPYRTLVLLNSFVAQPFLDPWVLLFCRTCVYTNSAVNPVVYSLMSQKFRAAFLKLCWCRAAGPQRRAARVLTSNYSAAQETSEGTEKM
  
Inhibitor
Name:
BDBM50261685
Synonyms:
CHEMBL447346 | corymbone A
Type:
Small organic molecule
Emp. Form.:
C35H38O7
Mol. Mass.:
570.672
SMILES:
Cc1c(O)c(C(CCc2ccccc2)C2C(=O)C(C)(C)C(=O)C(C)(C)C2=O)c(O)c(C(=O)CCc2ccccc2)c1O
Structure:
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