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Target
Egl nine homolog 1
Ligand
BDBM50324528
Substrate
n/a
Meas. Tech.
ChEMBL_649379 (CHEMBL1219077)
IC50
>100000±n/a nM
Citation
 Hamada, S; Suzuki, T; Mino, K; Koseki, K; Oehme, F; Flamme, I; Ozasa, H; Itoh, Y; Ogasawara, D; Komaarashi, H; Kato, A; Tsumoto, H; Nakagawa, H; Hasegawa, M; Sasaki, R; Mizukami, T; Miyata, N Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors. J Med Chem 53:5629-38 (2010) [PubMed]  Article 
Target
Name:
Egl nine homolog 1
Synonyms:
C1orf12 | EGLN1 | EGLN1_HUMAN | Egl nine homolog 1 (EGLN1) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIFPH2) | Prolyl hydroxylase domain-containing protein 2 (PHD2)
Type:
Protein
Mol. Mass.:
46035.59
Organism:
Homo sapiens (Human)
Description:
Q9GZT9
Residue:
426
Sequence:
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDSVGKDVF
  
Inhibitor
Name:
BDBM50324528
Synonyms:
3-({9-[Butyl(methyl)]amino}nonanoyl(hydroxy)amino)propanoicAcid Hydrochloride | CHEMBL1215588
Type:
Small organic molecule
Emp. Form.:
C17H34N2O4
Mol. Mass.:
330.4629
SMILES:
CCCCN(C)CCCCCCCCC(=O)N(O)CCC(O)=O
Structure:
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