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Target
Kappa-type opioid receptor
Ligand
BDBM50326197
Substrate
n/a
Meas. Tech.
ChEMBL_659318 (CHEMBL1247782)
Ki
1800±n/a nM
Citation
 Sakurada, T; Gill, MB; Frausto, S; Copits, B; Noguchi, K; Shimamoto, K; Swanson, GT; Sakai, R Novel N-methylated 8-oxoisoguanines from Pacific sponges with diverse neuroactivities. J Med Chem 53:6089-99 (2010) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50326197
Synonyms:
1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin-6(7H)-iminium chloride | CHEMBL1241328
Type:
Small organic molecule
Emp. Form.:
C7H9N5O2
Mol. Mass.:
195.1787
SMILES:
Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O
Structure:
Search PDB for entries with ligand similarity: