Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50429538
Substrate
n/a
Meas. Tech.
ChEMBL_2296945
Ki
20±n/a nM
Citation
 Conroy, S; Kindon, N; Kellam, B; Stocks, MJ Drug-like Antagonists of P2Y Receptors-From Lead Identification to Drug Development. J Med Chem 59:9981-10005 (2016) [PubMed] 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50429538
Synonyms:
CHEMBL2333767
Type:
Small organic molecule
Emp. Form.:
C23H25N3OS
Mol. Mass.:
391.529
SMILES:
Cc1ccc(NC(=O)Nc2cccnc2Sc2ccccc2C(C)(C)C)cc1
Structure:
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