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Target
von Hippel-Lindau disease tumor suppressor
Ligand
BDBM454910
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay (10% DMSO)
IC50
349±n/a nM
Citation
Crew, AP; Crews, CM; Chen, X; Dong, H; Ferraro, C; Qian, Y; Siu, K; Wang, J; Jin, M; Berlin, M; Zimmermann, K; Snyder, L Compounds and methods for the enhanced degradation of targeted proteins US Patent US10730870 Publication Date 8/4/2020
More Info.:
Target
Name:
von Hippel-Lindau disease tumor suppressor
Synonyms:
Protein G7 | VHL | VHL_HUMAN | Von Hippel-Lindau disease tumor suppressor | Von Hippel-Lindau disease tumor suppressor protein (VBC) | pVHL
Type:
Protein
Mol. Mass.:
24136.87
Organism:
Homo sapiens (Human)
Description:
P40337
Residue:
213
Sequence:
MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD