Reaction Details Report a problem with these data
Target
E3 ubiquitin-protein ligase XIAP [265-330]
Ligand
BDBM518282
Substrate
n/a
Meas. Tech.
Biological Assay
Ki
<25000±n/a nM
Citation
 Cosford, ND; Vamos, MD Inhibitor of apoptosis protein (IAP) antagonists US Patent  US11111270 Publication Date 9/7/2021 
Target
Name:
E3 ubiquitin-protein ligase XIAP [265-330]
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP/ BIR 3 | IAP3 | XIAP | XIAP_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
7652.55
Organism:
Homo sapiens (Human)
Description:
P98170[265-330]
Residue:
66
Sequence:
YEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYL
  
Inhibitor
Name:
BDBM518282
Synonyms:
US11111270, Compound 20 | US11111270, Compound 21
Type:
Small organic molecule
Emp. Form.:
C26H37N5O4
Mol. Mass.:
483.6031
SMILES:
CN[C@@H](C)C(=O)N[C@H]1CCCN(C2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12)C(C)=O |r,w:13.12,19.20|
Structure:
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