Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM48804
Substrate
n/a
Meas. Tech.
Homologous Recombination_Rad51_DNA binding assay
IC50
42500±n/a nM
Citation
 PubChem, PC Homologous Recombination_Rad51_DNA binding assay PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM48804
Synonyms:
3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-quinazolinone | 3-(phenylmethyl)-2-[(E)-2-pyridin-3-ylethenyl]quinazolin-4-one | 3-benzyl-2-[(E)-2-(3-pyridyl)vinyl]quinazolin-4-one | 3-benzyl-2-[(E)-2-pyridin-3-ylethenyl]quinazolin-4-one | MLS000709026 | SMR000289793 | cid_5738263
Type:
Small organic molecule
Emp. Form.:
C22H17N3O
Mol. Mass.:
339.3899
SMILES:
O=c1n(Cc2ccccc2)c(\C=C\c2cccnc2)nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: