Reaction Details Report a problem with these data
Target
Histone deacetylase
Ligand
BDBM50082666
Substrate
n/a
Meas. Tech.
ChEMBL_306475 (CHEMBL829553)
IC50
153±n/a nM
Citation
 Heltweg, B; Dequiedt, F; Marshall, BL; Brauch, C; Yoshida, M; Nishino, N; Verdin, E; Jung, M Subtype selective substrates for histone deacetylases. J Med Chem 47:5235-43 (2004) [PubMed]  Article 
Target
Name:
Histone deacetylase
Synonyms:
Hdac5 | Hdac5 protein
Type:
PROTEIN
Mol. Mass.:
34754.92
Organism:
Rattus norvegicus
Description:
ChEMBL_104809
Residue:
328
Sequence:
MHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYDDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPSINAVATLEKVIEIQSKHWSCVQRFATGLGCSLREAQTGEKEEAETVSAMALLSMGAEQAQAAATQEHSPRPAEEPMEQEPAL
  
Inhibitor
Name:
BDBM50082666
Synonyms:
4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]benzenecarboxamide | 4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benzamide | CHEMBL46942
Type:
Small organic molecule
Emp. Form.:
C15H23N3O3
Mol. Mass.:
293.3614
SMILES:
CN(C)c1ccc(cc1)C(=O)NCCCCCC(=O)NO
Structure:
Search PDB for entries with ligand similarity: