Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ac-KRSK-MCA peptide/SAM as substrate preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against histone deacetylases (HDAC1) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
Affinity DataIC50: 0.625nMAssay Description:Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC1 by fluorimetric assay in presence of DTTMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against histone deacetylase (HDAC4) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10(Mus musculus)
Institute Of Technology
Curated by ChEMBL
Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human HDAC4 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cells; Not testedMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HDAC4 by fluorimetric assay in presence of DTTMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase(Rattus norvegicus)
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human HDAC4 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair