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Found 296 with Last Name = 'nishino' and Initial = 'n'
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Riken

Curated by ChEMBL
LigandPNGBDBM50017721(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ac-KRSK-MCA peptide/SAM as substrate preincubated fo...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Mus musculus (Mouse))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against histone deacetylases (HDAC1) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  0.625nMAssay Description:Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  1nMAssay Description:Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)
Affinity DataIC50:  1nMAssay Description:Inhibition of HDAC1 by fluorimetric assay in presence of DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222728(CHEMBL394261 | cyclo(-L-Am7(S2Py)-A2in-L-Ala-D-Pro...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222736(CHEMBL241555 | cyclo(-L-Am7(S2Py)-Aib-L-Ser(Bzl)-D...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222728(CHEMBL394261 | cyclo(-L-Am7(S2Py)-A2in-L-Ala-D-Pro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))
Affinity DataIC50:  2nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222730(CHEMBL393464 | cyclo(-L-Am7(S2Py)-L-2MePhe-L-Ala-D...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222735(CHEMBL390991 | cyclo(-L-Am7(S2Py)-D-A1in-L-Ala-D-P...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222735(CHEMBL390991 | cyclo(-L-Am7(S2Py)-D-A1in-L-Ala-D-P...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222729(CHEMBL391384 | cyclo(-L-Am7(S2Py)-Aib-L-Ph5-D-Pro-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)
Affinity DataIC50:  3nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Mus musculus)
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against histone deacetylase (HDAC4) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))
Affinity DataIC50:  3.20nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222736(CHEMBL241555 | cyclo(-L-Am7(S2Py)-Aib-L-Ser(Bzl)-D...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222738(CHEMBL391383 | cyclo(-L-Am7(S2Py)-Aib-L-Ph4-D-Pro-...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50:  3.40nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222730(CHEMBL393464 | cyclo(-L-Am7(S2Py)-L-2MePhe-L-Ala-D...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222733(CHEMBL393961 | cyclo(-L-Am7(S2Py)-Aib-L-Ser-D-Pro-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10(Mus musculus)
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50221738(CHEMBL1790595)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50048860(CHEMBL3310508)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human HDAC4 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222737(CHEMBL238587 | cyclo(-L-Am7(S2Py)-Aib-L-Ala-D-Tic-...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222737(CHEMBL238587 | cyclo(-L-Am7(S2Py)-Aib-L-Ala-D-Tic-...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Cryptosporidium parvum)
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50366969(CHEMBL1790593)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cells; Not testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50048860(CHEMBL3310508)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))
Affinity DataIC50:  4.90nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309932(6-((1R,14S,20R,23S)-15,21,24,26-Tetraoxo-16,22,25,...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222729(CHEMBL391384 | cyclo(-L-Am7(S2Py)-Aib-L-Ph5-D-Pro-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309929(6-((1S,7R,10S,13R)-2,8,11,24-Tetraoxo-3,9,12,23-te...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50394110(CHEMBL2158742)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of HDAC4 by fluorimetric assay in presence of DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222738(CHEMBL391383 | cyclo(-L-Am7(S2Py)-Aib-L-Ph4-D-Pro-...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222733(CHEMBL393961 | cyclo(-L-Am7(S2Py)-Aib-L-Ser-D-Pro-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50:  7.5nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50048859(CHEMBL3310507)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50:  8.20nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50048859(CHEMBL3310507)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of human HDAC4 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222728(CHEMBL394261 | cyclo(-L-Am7(S2Py)-A2in-L-Ala-D-Pro...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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