Reaction Details Report a problem with these data
Target
Ecdysone receptor
Ligand
BDBM50488447
Substrate
n/a
Meas. Tech.
ChEMBL_923770 (CHEMBL3070748)
EC50
>100000±n/a nM
Citation
 Soin, T; De Geyter, E; Mosallanejad, H; Iga, M; Martín, D; Ozaki, S; Kitsuda, S; Harada, T; Miyagawa, H; Stefanou, D; Kotzia, G; Efrose, R; Labropoulou, V; Geelen, D; Iatrou, K; Nakagawa, Y; Janssen, CR; Smagghe, G; Swevers, L Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. Pest Manag Sci 66:526-35 (2010) [PubMed]  Article 
Target
Name:
Ecdysone receptor
Synonyms:
Ecdysone receptor
Type:
PROTEIN
Mol. Mass.:
65589.52
Organism:
Spodoptera littoralis
Description:
ChEMBL_105550
Residue:
585
Sequence:
MSIESRLDSLVRGKSEVKAFAGGCPSALLDTGACDTLADMRRRWYNNGGFQTLRMLEESSSEVTSSSALGLPPAMVMSPESLASPEYGGLELWGYEDGLTTYSMAQSLGSCTMEQQQQPQQQQQPQQTQPLPSMPLPMPPTTPKSENESMSSGREELSPASSVNGCSTDGEARRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRKEKKAQREKDKLPVSTTTVDDHMPPIMQCDPPPPEAARIHEVVPRFLTEKILEQNRLKNVPPLTTNQKSLIARLVWYQEGYEQPSEEDLKRVTQSDEDDEESDMPFRQITEMTILTVQLIVEFAKGLPGFAKISQSDQITLLKACSSEVMMLRVARRYDASTDSVLFANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYAMSMDNVQYALLTAIVIFSDRPGLEQPLLVEEIQRYYLNTLRMYVLNQHSASPRCPVVFGKILGVLTELRTLGMQNSNMCISLKLKNRKLPPFLEEIWDVADVSTTATPAAPVTETAAL
  
Inhibitor
Name:
BDBM50488447
Synonyms:
CHEMBL2286412
Type:
Small organic molecule
Emp. Form.:
C17H20F3NO2
Mol. Mass.:
327.3414
SMILES:
Cc1cc(C)cc(c1)C(=O)C1(CCCCC1)NC(=O)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: