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Target
Beta-lactamase
Ligand
BDBM50033687
Substrate
n/a
Meas. Tech.
ChEMBL_40540 (CHEMBL652170)
IC50
>20000±n/a nM
Citation
 Buynak, JD; Wu, K; Bachmann, B; Khasnis, D; Hua, L; Nguyen, HK; Carver, CL Synthesis and biological activity of 7-alkylidenecephems. J Med Chem 38:1022-34 (1995) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ENTCL | ampC
Type:
PROTEIN
Mol. Mass.:
41306.67
Organism:
Enterobacter cloacae
Description:
ChEMBL_40258
Residue:
381
Sequence:
MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHYYTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQWQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGALAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQAYGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEANTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLANTSYPNPARVEAAYHILEALQ
  
Inhibitor
Name:
BDBM50033687
Synonyms:
CHEMBL8259 | Sodium; (R)-3-acetoxymethyl-7-dichloromethylene-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C11H8Cl2NO5S
Mol. Mass.:
337.156
SMILES:
[#6]-[#6](=O)-[#8]-[#6]-[#6]-1=[#6](-[#7]-2-[#6@H](-[#16]-[#6]-1)\[#6](=[#6](\Cl)Cl)-[#6]-2=O)-[#6](-[#8-])=O |t:5|
Structure:
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