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Target
Serine protease 1
Ligand
BDBM50066612
Substrate
n/a
Meas. Tech.
ChEMBL_212379 (CHEMBL817625)
Ki
410±n/a nM
Citation
 Shaw, KJ; Guilford, WJ; Dallas, JL; Koovakkaat, SK; McCarrick, MA; Liang, A; Light, DR; Morrissey, MM (Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa. J Med Chem 41:3551-6 (1998) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50066612
Synonyms:
(E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-one | 2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylidene]-1-cycloheptanone | CHEMBL326552
Type:
Small organic molecule
Emp. Form.:
C23H24N4O
Mol. Mass.:
372.4629
SMILES:
NC(=N)c1cccc(\C=C2/CCCC\C(=C/c3cccc(c3)C(N)=N)C2=O)c1
Structure:
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