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Target
Cytochrome P450 2C9
Ligand
BDBM50520561
Substrate
n/a
Meas. Tech.
ChEMBL_1880729 (CHEMBL4382123)
IC50
>200000±n/a nM
Citation
 Chen, W; Yuan, X; Li, Z; Lu, Z; Kong, S; Jiang, H; Du, H; Pan, X; Nandi, M; Kong, X; Brown, K; Liu, Z; Zhang, G; Hider, RC; Yu, Y CN128: A New Orally Active Hydroxypyridinone Iron Chelator. J Med Chem 63:4215-4226 (2020) [PubMed]  Article 
Target
Name:
Cytochrome P450 2C9
Synonyms:
(R)-limonene 6-monooxygenase | (S)-limonene 6-monooxygenase | CP2C9_HUMAN | CYP2C10 | CYP2C9 | CYPIIC9 | Cytochrome P450 2C9 (CYP2C9 ) | Cytochrome P450 2C9 (CYP2C9) | P-450MP | P450 MP-4/MP-8 | P450 PB-1 | S-mephenytoin 4-hydroxylase
Type:
Enzyme
Mol. Mass.:
55636.33
Organism:
Homo sapiens (Human)
Description:
P11712
Residue:
490
Sequence:
MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV
  
Inhibitor
Name:
BDBM50520561
Synonyms:
CHEMBL4467408
Type:
Small organic molecule
Emp. Form.:
C15H18ClNO3
Mol. Mass.:
295.761
SMILES:
[Cl-].Cc1c(O)c(O)cc[n+]1[C@@H](CO)Cc1ccccc1 |r|
Structure:
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