Reaction Details Report a problem with these data
Target
Free fatty acid receptor 3
Ligand
BDBM50527469
Substrate
n/a
Meas. Tech.
ChEMBL_1902654 (CHEMBL4404876)
EC50
1349±n/a nM
Citation
 Ulven, ER; Quon, T; Sergeev, E; Barki, N; Brvar, M; Hudson, BD; Dutta, P; Hansen, AH; Bielefeldt, LŲ; Tobin, AB; McKenzie, CJ; Milligan, G; Ulven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem 63:3577-3595 (2020) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 3
Synonyms:
FFAR3_RAT | Ffar3 | Free fatty acid receptor 3 | G-protein coupled receptor 41 | Gpr41
Type:
PROTEIN
Mol. Mass.:
36493.02
Organism:
Rattus norvegicus
Description:
ChEMBL_117217
Residue:
319
Sequence:
MDTSFFPGNHWLFFSVDLLVFLVGLPLNVMALVVFVNKLRRRPVAVDLLLLNLTISDLLLLLFLPFRIVEAACGMKWILPFIFCPLSGFLFFTTIYLTSLFLMTVSIERFLSVAYPLWYKTRPRLAQAGLVSGICWFLASAHCSVIYVTEYWGNATYSQGTNGTCYLEFREDQLAILLPVRLEMAVVLFMVPLCITSYCYSRLVWILSQGASRRRRKRVMGLLVATLLIFFVCFGPYNMSHVVGYVRGESPTWRSYVLLLSTLNSCIDPLVFYFSSSKFQADFHQLLSRLIRACVPWTQEVSLELKVKNGEEPSKECPS
  
Inhibitor
Name:
BDBM50527469
Synonyms:
CHEMBL4448591
Type:
Small organic molecule
Emp. Form.:
C22H22N2O3
Mol. Mass.:
362.4217
SMILES:
CC1=C(C(c2ccco2)C2=C(CCCC2=O)N1)C(=O)Nc1ccccc1C |t:1,10|
Structure:
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