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Target
Adenosine receptor A3
Ligand
BDBM50116380
Substrate
n/a
Meas. Tech.
ChEMBL_31694 (CHEMBL876574)
Ki
213±n/a nM
Citation
 Priego, EM; von Frijtag Drabbe Kuenzel, J; IJzerman, AP; Camarasa, MJ; Pérez-Pérez, MJ Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists. J Med Chem 45:3337-44 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50116380
Synonyms:
1-Benzyl-3-(4-methoxy-benzyl)-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione | CHEMBL114127
Type:
Small organic molecule
Emp. Form.:
C24H20N4O3
Mol. Mass.:
412.4406
SMILES:
COc1ccc(Cn2c(=O)n(Cc3ccccc3)c3nc4ccccn4c3c2=O)cc1
Structure:
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