Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50119133
Substrate
n/a
Meas. Tech.
ChEMBL_30140 (CHEMBL640587)
Ki
1280±n/a nM
Citation
 Palle, VP; Elzein, EO; Gothe, SA; Li, Z; Gao, Z; Meyer, S; Blackburn, B; Zablocki, JA Structure-affinity relationships of the affinity of 2-pyrazolyl adenosine analogues for the adenosine A2A receptor. Bioorg Med Chem Lett 12:2935-9 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50119133
Synonyms:
(2R,3R,4S,5R)-2-{6-Amino-2-[1-(3-phenyl-propyl)-1H-pyrazol-4-yl]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL100348
Type:
Small organic molecule
Emp. Form.:
C22H25N7O4
Mol. Mass.:
451.4784
SMILES:
Nc1nc(nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)-c1cnn(CCCc2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: