Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50190700
Substrate
n/a
Meas. Tech.
ChEMBL_369241 (CHEMBL864795)
Ki
98±n/a nM
Citation
 Yan, L; Bertarelli, DC; Hayallah, AM; Meyer, H; Klotz, KN; Müller, CE A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists. J Med Chem 49:4384-91 (2006) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50190700
Synonyms:
8-[4-(2-hydroxyethylamidosulfonyl)phenyl]-1,3-dimethylxanthine | CHEMBL377106
Type:
Small organic molecule
Emp. Form.:
C15H17N5O5S
Mol. Mass.:
379.391
SMILES:
Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(cc1)S(=O)(=O)NCCO
Structure:
Search PDB for entries with ligand similarity: