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Target
Carbonic anhydrase 7
Ligand
BDBM50612164
Substrate
n/a
Meas. Tech.
ChEMBL_2286192
Ki
37±n/a nM
Citation
 Ghatpande, NG; Jadhav, JS; Kaproormath, RV; Soliman, ME; Shaikh, MM A brief overview on recent advances in spiro[chromane-2,4'-piperidine]-4(3H)-one-functionalized compounds in medicinal chemistry research. Bioorg Med Chem 28:0 (2020) [PubMed] 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50612164
Synonyms:
CHEMBL5285561
Type:
Small organic molecule
Emp. Form.:
C19H19N3O6S
Mol. Mass.:
417.436
SMILES:
NS(=O)(=O)c1ccc(N2CCC3(CC2)CC(=O)c2ccccc2O3)c(c1)[N+]([O-])=O
Structure:
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