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Target
Carbonic anhydrase 7
Ligand
BDBM50612168
Substrate
n/a
Meas. Tech.
ChEMBL_2286192
Ki
76±n/a nM
Citation
 Ghatpande, NG; Jadhav, JS; Kaproormath, RV; Soliman, ME; Shaikh, MM A brief overview on recent advances in spiro[chromane-2,4'-piperidine]-4(3H)-one-functionalized compounds in medicinal chemistry research. Bioorg Med Chem 28:0 (2020) [PubMed] 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50612168
Synonyms:
CHEMBL5268000
Type:
Small organic molecule
Emp. Form.:
C22H25N3O7S
Mol. Mass.:
475.515
SMILES:
CCCOc1ccc2OC3(CCN(CC3)c3ccc(cc3[N+]([O-])=O)S(N)(=O)=O)CC(=O)c2c1
Structure:
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