Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50215908
Substrate
n/a
Meas. Tech.
ChEMBL_447762 (CHEMBL896771)
Ki
487±n/a nM
Citation
 Xia, Y; Chackalamannil, S; Clasby, M; Doller, D; Eagen, K; Greenlee, WJ; Tsai, H; Agans-Fantuzzi, J; Ahn, HS; Boykow, GC; Hsieh, Y; Lunn, CA; Chintala, M Himbacine derived thrombin receptor (PAR-1) antagonists: SAR of the pyridine ring. Bioorg Med Chem Lett 17:4509-13 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50215908
Synonyms:
(3R,3aS,4S,4aR,8aS,9aR,E)-3-methyl-4-(2-(5-(pyrrolidin-1-yl)pyridin-2-yl)vinyl)-decahydronaphtho[2,3-c]furan-1(3H)-one | CHEMBL233343
Type:
Small organic molecule
Emp. Form.:
C24H32N2O2
Mol. Mass.:
380.5231
SMILES:
C[C@H]1OC(=O)[C@@H]2C[C@@H]3CCCC[C@H]3[C@H](\C=C\c3ccc(cn3)N3CCCC3)[C@H]12
Structure:
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